🧪 Urinary Test Strips (Dipstick)
A practical guide to bedside urinalysis – parameters, interpretation, and clinical use.
📋 Overview of test strips
Proper technique for dipstick testing
A variety of test strips for urinalysis are available. Some have a specific purpose, e.g.:
- Clinistix® – glucose
- Hemastix® – blood
- Albustix® – albumin
Others cast a wider net, combining multiple parameters:
Specific gravity
pH
Leucocytes
Nitrites
Glucose
Urobilinogen
Bilirubin
Ketones
Protein / Albumin
Blood
🍬 Glucose (glycosuria)
- Glycosuria results when tubular reabsorptive capacity for glucose is exceeded – typically plasma glucose > 10 mmol/L.
- A valuable screening tool, but less useful for diagnosis and monitoring of diabetes mellitus.
- Renal glycosuria occurs when proximal tubular injury leads to failure to reabsorb filtered glucose (normal plasma glucose).
🥚 Protein (proteinuria)
- Dipsticks are convenient and highly specific but less sensitive than quantitative methods.
- They contain pH‑sensitive indicators that change colour when bound to negatively charged proteins – predominantly albumin (may not detect Bence‑Jones proteins).
- Dipsticks have superseded sulphosalicylic acid turbidity testing.
- A positive result occurs with protein excretion >300 mg/L.
- Lower amounts (microalbuminuria: 30–300 mg/day) require specific immunoassays or sensitive dipsticks, especially in diabetes.
Semi‑quantitative dipstick protein results
| Result | Estimated quantity (g/L) |
|---|---|
| Trace | 0.15–0.3 |
| + | 0.3 |
| ++ | 1.0 |
| +++ | 2.5–5.0 |
| ++++ | >10 |
📌 Persistent dipstick proteinuria (≥1+) requires confirmation with urine protein‑to‑creatinine ratio (uPCR) or albumin‑to‑creatinine ratio (uACR).
📚 Learn more
For a complete reference on urine appearance, microscopy, casts and crystals, visit:
🔬 More details about urine examination →